| Gene Information | |
|---|---|
| Gene Name | GH1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 217 |
| Protein Names | Somatotropin (Growth hormone) (GH) (GH-N) (Growth hormone 1) (Pituitary growth hormone) |
| Target Name | somatotropin |
| Target Type | Clinical trial target |
| Gene Age | 544 ( ENSG00000259384 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P01241 |
| Gene Card | GH1 |
| Uniprot ID | P01241 |
| Pfam | PF00103 |
| In ASD | no |
| Allosteric Prediction | yes (0.770115339) |
| Ortholog in Animals | Dog_ GH1 ( ortholog_one2many ) GuineaPig_ GHB1 ( ortholog_one2many ) Mouse_ Gh ( ortholog_one2many ) Rat_ Gh1 ( ortholog_one2many ) Rabbit_ GHB1 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | GH2, CSH2, CSH1, CSHL1, PRL |
| Tissue | pituitary.gland |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1A22 (X-ray 2.60A ) 1AXI (X-ray 2.10A ) 1BP3 (X-ray 2.90A ) 1HGU (X-ray 2.50A ) 1HUW (X-ray 2.00A ) 1HWG (X-ray 2.50A ) 1HWH (X-ray 2.90A ) 1KF9 (X-ray 2.60A ) 3HHR (X-ray 2.80A ) 6QIO (X-ray 1.95A ) |
| DBSNP | rs2001345 rs71640273 rs71640276 rs137853222 rs137853220 rs6174 rs5388 rs137853221 rs148474991 rs137853223 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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