| Gene Information | |
|---|---|
| Gene Name | INTS6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 887 |
| Protein Names | Integrator complex subunit 6 (Int6) (DBI-1) (Protein DDX26) (Protein deleted in cancer 1) (DICE1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 424 ( ENSG00000102786 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UL03 |
| Gene Card | INTS6 |
| Uniprot ID | Q9UL03 |
| Pfam | PF15300; PF13519 |
| In ASD | no |
| Allosteric Prediction | no (-0.542716347) |
| Ortholog in Animals | Alpaca_ INTS6 ( ortholog_one2one ) Dog_ INTS6 ( ortholog_one2one ) GuineaPig_ INTS6 ( ortholog_one2one ) Mouse_ Ints6 ( ortholog_one2one ) Pig_ INTS6 ( ortholog_one2one ) Rat_ Ints6 ( ortholog_one2one ) Rabbit_ INTS6 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CT45A1, SAGE1, CT45A7, CT45A3, CT45A8, CT45A2, CT45A9, CT45A10, CT45A6, CT45A5, INTS6L |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:10467397}. |
| Pharmacological Animal Models | 0.047047(Chimpanzee);0.031687(Mouse);NULL(Rat);0.169091(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7BV7 (X-ray 2.40A ) 7CUN (EM 3.50A ) 7PKS (EM 3.60A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:11939413, ECO:0000269|PubMed:23904267}. |
| Mouse PG classification | NA |
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