| Gene Information | |
|---|---|
| Gene Name | GGT5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 586 |
| Protein Names | Glutathione hydrolase 5 proenzyme (EC 3.4.19.13) (Gamma-glutamyl transpeptidase-related enzyme) (GGT-rel) (Gamma-glutamyltransferase 5) (GGT 5) (EC 2.3.2.2) (Gamma-glutamyltransferase-like activity 1) (Gamma-glutamyltranspeptidase 5) (Leukotriene-C4 hydrolase) (EC 3.4.19.14) [Cleaved into: Glutathione hydrolase 5 heavy chain; Glutathione hydrolase 5 light chain] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000099998 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P36269 |
| Gene Card | GGT5 |
| Uniprot ID | P36269 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | yes (0.106552338) |
| Ortholog in Animals | Alpaca_ GGT5 ( ortholog_one2one ) GuineaPig_ GGT5 ( ortholog_one2one ) Macaque_ GGT5 ( ortholog_one2one ) Mouse_ Ggt5 ( ortholog_one2one ) Pig_ GGT5 ( ortholog_one2one ) Rat_ AABR07044631.2 ( ortholog_one2one ) Rabbit_ GGT5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GGT7, GGT6, GGT1, GGTLC3, GGTLC2, GGTLC1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs5760274 rs2275984 rs6004105 rs7288201 |
| Subcellular location [CC] | Membrane {ECO:0000250|UniProtKB:Q9Z2A9}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q9Z2A9}. |
| Mouse PG classification | NA |
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