| Gene Information | |
|---|---|
| Gene Name | GGCX |
| Organism | Homo sapiens (Human) |
| Gene Length | 758 |
| Protein Names | Vitamin K-dependent gamma-carboxylase (EC 4.1.1.90) (Gamma-glutamyl carboxylase) (Peptidyl-glutamate 4-carboxylase) (Vitamin K gamma glutamyl carboxylase) |
| Target Name | vitamin k-dependent gamma-carboxylase |
| Target Type | Successful target |
| Gene Age | 680 ( ENSG00000115486 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P38435 |
| Gene Card | GGCX |
| Uniprot ID | P38435 |
| Pfam | PF05090 |
| In ASD | no |
| Allosteric Prediction | yes (0.395296167) |
| Ortholog in Animals | Alpaca_ GGCX ( ortholog_one2one ) Dog_ GGCX ( ortholog_one2one ) GuineaPig_ GGCX ( ortholog_one2one ) Macaque_ GGCX ( ortholog_one2one ) Mouse_ Ggcx ( ortholog_one2one ) Pig_ GGCX ( ortholog_one2one ) Rat_ Ggcx ( ortholog_one2one ) Rabbit_ GGCX ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs121909677 rs699664 rs121909675 rs121909681 rs121909682 rs121909676 rs121909679 rs28928872 rs121909678 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:10910912}; Multi-pass membrane protein {ECO:0000269|PubMed:10910912}. |
| Mouse PG classification | NA |
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