| Gene Information | |
|---|---|
| Gene Name | GGA2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 613 |
| Protein Names | ADP-ribosylation factor-binding protein GGA2 (Gamma-adaptin-related protein 2) (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000103365 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9UJY4 |
| Gene Card | GGA2 |
| Uniprot ID | Q9UJY4 |
| Pfam | PF02883; PF03127; PF18308; PF00790 |
| In ASD | no |
| Allosteric Prediction | no (-0.302649378) |
| Ortholog in Animals | Alpaca_ GGA2 ( ortholog_one2one ) Dog_ GGA2 ( ortholog_one2one ) GuineaPig_ GGA2 ( ortholog_one2one ) Macaque_ GGA2 ( ortholog_one2one ) Mouse_ Gga2 ( ortholog_one2one ) Pig_ GGA2 ( ortholog_one2one ) Rat_ Gga2 ( ortholog_one2one ) Rabbit_ GGA2 ( ortholog_one2one ) |
| Ohnologs | GGA1, GGA3 |
| Paralogs | WDFY2, STAM2, HGS, GGA1, TOM1, WDFY1, TOM1L2, GGA3, STAM, TOM1L1 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.025(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 1MHQ (X-ray 2.20A ) |
| DBSNP | rs1135045 |
| Subcellular location [CC] | Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:10749927, ECO:0000269|PubMed:15039775, ECO:0000269|PubMed:28289207}; Peripheral membrane protein {ECO:0000269|PubMed:10749927, ECO:0000269|PubMed:15039775}. Endosome membrane {ECO:0000269|PubMed:15039775}; Peripheral membrane protein {ECO:0000269|PubMed:15039775}. Early endosome membrane {ECO:0000269|PubMed:11950392}; Peripheral membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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