| Gene Information | |
|---|---|
| Gene Name | GGA1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 639 |
| Protein Names | ADP-ribosylation factor-binding protein GGA1 (Gamma-adaptin-related protein 1) (Golgi-localized, gamma ear-containing, ARF-binding protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000100083 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UJY5 |
| Gene Card | GGA1 |
| Uniprot ID | Q9UJY5 |
| Pfam | PF02883; PF03127; PF18308; PF00790 |
| In ASD | no |
| Allosteric Prediction | no (-0.825025701) |
| Ortholog in Animals | Alpaca_ GGA1 ( ortholog_one2one ) Dog_ GGA1 ( ortholog_one2one ) GuineaPig_ GGA1 ( ortholog_one2one ) Macaque_ GGA1 ( ortholog_one2one ) Mouse_ Gga1 ( ortholog_one2one ) Pig_ GGA1 ( ortholog_one2one ) Rat_ Gga1 ( ortholog_one2one ) |
| Ohnologs | GGA2, GGA3 |
| Paralogs | WDFY2, STAM2, HGS, TOM1, WDFY1, TOM1L2, GGA3, STAM, GGA2, TOM1L1 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 1J2J (X-ray 1.60A ) 1JWF (X-ray 2.10A ) 1JWG (X-ray 2.00A ) 1NA8 (X-ray 2.30A ) 1NAF (X-ray 2.80A ) 1NWM (X-ray 2.40A ) 1O3X (X-ray 2.10A ) 1OM9 (X-ray 2.50A ) 1OXZ (X-ray 2.80A ) 1PY1 (X-ray 2.60A ) 1UJJ (X-ray 2.60A ) 1UJK (X-ray 1.90A ) 1X79 (X-ray 2.41A ) 2DWX (X-ray 2.55A ) 2DWY (X-ray 2.30A ) 3G2S (X-ray 1.70A ) 3G2T (X-ray 2.00A ) 3G2U (X-ray 2.30A ) 3G2V (X-ray 2.10A ) 3G2W (X-ray 2.40A ) |
| DBSNP | rs765255006 |
| Subcellular location [CC] | Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:15886016}; Peripheral membrane protein. Endosome membrane {ECO:0000269|PubMed:15886016}; Peripheral membrane protein. Early endosome membrane {ECO:0000269|PubMed:15886016}; Peripheral membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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