Gene Information
Gene NameGFUS
OrganismHomo sapiens (Human)
Gene Length321
Protein NamesGDP-L-fucose synthase (EC 1.1.1.271) (GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase) (Protein FX) (Red cell NADP(H)-binding protein) (Short-chain dehydrogenase/reductase family 4E member 1)
Target NameNA
Target TypeNA
Gene Age1488 ( ENSG00000104522 )
3 ( ENSG00000278243 )
Evolutionary StageEuk+Bac
AlphaFoldDBQ13630
Gene CardGFUS
Uniprot IDQ13630
PfamPF01370
In ASDno
Allosteric Predictionyes (0.083669414)
Ortholog in AnimalsAlpaca_ GFUS ( ortholog_one2one )
Dog_ GFUS ( ortholog_one2one )
GuineaPig_ GFUS ( ortholog_one2one )
Macaque_ GFUS ( ortholog_one2one )
Mouse_ Gfus ( ortholog_one2one )
Pig_ GFUS ( ortholog_one2one )
Rat_ Gfus ( ortholog_one2one )
OhnologsNA
ParalogsHSD3B7, HSD3B2, HSD3B1, SDR42E2, GALE, SDR42E1, GMDS, TGDS, UXS1, NSDHL
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 4B8W  (X-ray  2.75A  4B8Z  (X-ray  2.75A  4BKP  (X-ray  2.70A  4BL5  (X-ray  2.60A  4E5Y  (X-ray  2.37A 
DBSNP NA 
Subcellular location [CC]NA
Mouse PG classificationNA
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