| Gene Information | |
|---|---|
| Gene Name | MS4A8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 250 |
| Protein Names | Membrane-spanning 4-domains subfamily A member 8 (Four-span transmembrane protein 4) (Membrane-spanning 4-domains subfamily A member 8B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000166959 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q9BY19 |
| Gene Card | MS4A8 |
| Uniprot ID | Q9BY19 |
| Pfam | PF04103 |
| In ASD | no |
| Allosteric Prediction | no (-1.588771774) |
| Ortholog in Animals | Alpaca_ MS4A8 ( ortholog_one2one ) Macaque_ MS4A8 ( ortholog_one2one ) Mouse_ Ms4a8a ( ortholog_one2one ) Pig_ MS4A8 ( ortholog_one2one ) Rat_ Ms4a8 ( ortholog_one2one ) Rabbit_ MS4A8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MS4A12, MS4A6E, MS4A6A, MS4A7, MS4A10, MS4A2, MS4A1, MS4A15, TMEM212, MS4A13, MS4A5, MS4A18, MS4A4E, MS4A4A, MS4A3, MS4A14 |
| Tissue | duodenum, oviduct, small.intestine, small.intestine.Peyers.patch |
| Tissue Specificity | Expressed by hematopoietic tissues and cells lines. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35956659 |
| Subcellular location [CC] | Membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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