| Gene Information | |
|---|---|
| Gene Name | DEFB102 |
| Organism | Homo sapiens (Human) |
| Gene Length | 64 |
| Protein Names | Defensin beta 4A (Beta-defensin 2) (BD-2) (hBD-2) (Defensin, beta 2) (Skin-antimicrobial peptide 1) (SAP1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O15263 |
| Gene Card | DEFB4A;DEFB4B |
| Uniprot ID | O15263 |
| Pfam | PF00711 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in lung epithelial cells (at protein level) (PubMed:10837369). Expressed in foreskin, lung and trachea (PubMed:9202117). Lower expression in kidney, uterus and salivary gland tissue (PubMed:9202117). Expressed in epithelial cells of the respiratory tract, with higher expression in distal parenchyma of the lung, trachea, and tonsils, and lower expression in pharynx and adenoid, and low expression in tongue and larynx (PubMed:9831658, PubMed:10837369). {ECO:0000269|PubMed:10837369, ECO:0000269|PubMed:9202117, ECO:0000269|PubMed:9831658}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 1E4Q (NMR - ) 1FD3 (X-ray 1.35A ) 1FD4 (X-ray 1.70A ) 1FQQ (NMR - ) 6CS9 (X-ray 1.85A ) |
| DBSNP | NA |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:10837369}. |
| Mouse PG classification | NA |
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