| Gene Information | |
|---|---|
| Gene Name | GFM2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 779 |
| Protein Names | Ribosome-releasing factor 2, mitochondrial (RRF2mt) (Elongation factor G 2, mitochondrial) (EF-G2mt) (mEF-G 2) (Elongation factor G2) (hEFG2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000164347 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q969S9 |
| Gene Card | GFM2 |
| Uniprot ID | Q969S9 |
| Pfam | PF00679; PF14492; PF03764; PF00009; PF03144 |
| In ASD | no |
| Allosteric Prediction | no (-1.145025764) |
| Ortholog in Animals | Alpaca_ GFM2 ( ortholog_one2one ) Dog_ GFM2 ( ortholog_one2one ) GuineaPig_ GFM2 ( ortholog_one2one ) Macaque_ GFM2 ( ortholog_one2one ) Mouse_ Gfm2 ( ortholog_one2one ) Pig_ GFM2 ( ortholog_one2one ) Rat_ Gfm2 ( ortholog_one2one ) Rabbit_ GFM2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | EFTUD2, EIF2S3, EIF2S3B, GTPBP1, GUF1, EIF5B, MTIF2, EEF2, EFL1, GSPT2, EEFSEC, EEF1A1, EEF1A2, HBS1L, GTPBP2, GFM1, GSPT1, TUFM |
| Tissue | NA |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:11735030}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7L20 (EM 3.15A ) 7NSH (EM 3.20A ) |
| DBSNP | rs957680 rs1554042187 rs761283105 rs16872235 rs17852780 rs17856872 rs17856871 rs1048167 |
| Subcellular location [CC] | Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03059}. |
| Mouse PG classification | NA |
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