| Gene Information | |
|---|---|
| Gene Name | GFM1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 751 |
| Protein Names | Elongation factor G, mitochondrial (EF-Gmt) (Elongation factor G 1, mitochondrial) (mEF-G 1) (Elongation factor G1) (hEFG1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000168827 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q96RP9 |
| Gene Card | GFM1 |
| Uniprot ID | Q96RP9 |
| Pfam | PF00679; PF14492; PF03764; PF00009; PF03144 |
| In ASD | no |
| Allosteric Prediction | no (-0.627604442) |
| Ortholog in Animals | Alpaca_ GFM1 ( ortholog_one2one ) Dog_ GFM1 ( ortholog_one2one ) GuineaPig_ GFM1 ( ortholog_one2one ) Macaque_ GFM1 ( ortholog_one2one ) Mouse_ Gfm1 ( ortholog_one2one ) Pig_ GFM1 ( ortholog_one2one ) Rat_ Gfm1 ( ortholog_one2one ) Rabbit_ GFM1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | EFTUD2, EIF2S3, EIF2S3B, GTPBP1, GUF1, EIF5B, MTIF2, EEF2, EFL1, GSPT2, EEFSEC, EEF1A1, EEF1A2, HBS1L, GTPBP2, GFM2, GSPT1, TUFM |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.173359(Rat);0.127126(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6VLZ (EM 2.97A ) 6VMI (EM 2.96A ) 6YDP (EM 3.00A ) 6YDW (EM 4.20A ) 7A5K (EM 3.70A ) |
| DBSNP | rs1254972325 rs119470018 rs2303909 rs139430866 rs119470020 |
| Subcellular location [CC] | Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03061}. |
| Mouse PG classification | NA |
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