| Gene Information | |
|---|---|
| Gene Name | GFI1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 422 |
| Protein Names | Zinc finger protein Gfi-1 (Growth factor independent protein 1) (Zinc finger protein 163) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 810 ( ENSG00000162676 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q99684 |
| Gene Card | GFI1 |
| Uniprot ID | Q99684 |
| Pfam | PF00096 |
| In ASD | no |
| Allosteric Prediction | no (-0.244682952) |
| Ortholog in Animals | Alpaca_ GFI1 ( ortholog_one2one ) Dog_ GFI1 ( ortholog_one2one ) GuineaPig_ GFI1 ( ortholog_one2one ) Macaque_ GFI1 ( ortholog_one2one ) Mouse_ Gfi1 ( ortholog_one2one ) Pig_ GFI1 ( ortholog_one2one ) Rat_ Gfi1 ( ortholog_one2one ) Rabbit_ GFI1 ( ortholog_one2one ) |
| Ohnologs | GFI1B |
| Paralogs | FEZF1, PRDM12, ZNF280A, ZBTB33, ZBTB21, ZNF280C, NACC2, ZNF580, ZBTB26, NACC1, ZNF683, ZBTB7B, PRDM13, ZNF280B, ZBTB6, ZBTB14, GFI1B, BCL6, ZBTB49, BCL6B, ZBTB3, ZNF581, FEZF2, ZNF280D, ZBTB46, ZNF524, ZBTB12, ZBTB25 |
| Tissue | bone.marrow |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34631763 rs28936381 rs28936382 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:11060035, ECO:0000269|PubMed:12874834, ECO:0000269|PubMed:18805794, ECO:0000269|PubMed:20547752, ECO:0000269|PubMed:8754800}. Note=Colocalizes with PIAS3 and RUNX1T1 in nuclear dots. |
| Mouse PG classification | HPG |
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