| Gene Information | |
|---|---|
| Gene Name | GFER |
| Organism | Homo sapiens (Human) |
| Gene Length | 205 |
| Protein Names | FAD-linked sulfhydryl oxidase ALR (EC 1.8.3.2) (Augmenter of liver regeneration) (hERV1) (Hepatopoietin) |
| Target Name | fad-linked sulfhydryl oxidase alr |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000127554 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P55789 |
| Gene Card | GFER |
| Uniprot ID | P55789 |
| Pfam | PF04777 |
| In ASD | no |
| Allosteric Prediction | no (-0.629549769) |
| Ortholog in Animals | Alpaca_ GFER ( ortholog_one2one ) Dog_ GFER ( ortholog_one2one ) GuineaPig_ GFER ( ortholog_one2one ) Macaque_ GFER ( ortholog_one2one ) Mouse_ Gfer ( ortholog_one2one ) Pig_ GFER ( ortholog_one2one ) Rat_ Gfer ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. Highest expression in the testis and liver and low expression in the muscle. {ECO:0000269|PubMed:19409522}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3MBG (X-ray 1.85A ) 3O55 (X-ray 1.90A ) 3TK0 (X-ray 1.61A ) 3U2L (X-ray 1.95A ) 3U2M (X-ray 2.00A ) 3U5S (X-ray 1.50A ) 4LDK (X-ray 2.04A ) |
| DBSNP | rs36041021 rs121908192 |
| Subcellular location [CC] | [Isoform 1]: Mitochondrion intermembrane space. Mitochondrion {ECO:0000269|PubMed:23676665}.; [Isoform 2]: Cytoplasm. Secreted. |
| Mouse PG classification | LPG |
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