| Gene Information | |
|---|---|
| Gene Name | GET3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 348 |
| Protein Names | ATPase GET3 (EC 3.6.-.-) (Arsenical pump-driving ATPase) (Arsenite-stimulated ATPase) (Guided entry of tail-anchored proteins factor 3, ATPase) (Transmembrane domain recognition complex 40 kDa ATPase subunit) (hARSA-I) (hASNA-I) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000198356 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | O43681 |
| Gene Card | GET3 |
| Uniprot ID | O43681 |
| Pfam | PF02374 |
| In ASD | no |
| Allosteric Prediction | yes (0.050767525) |
| Ortholog in Animals | Alpaca_ GET3 ( ortholog_one2one ) Dog_ GET3 ( ortholog_one2one ) GuineaPig_ GET3 ( ortholog_one2one ) Macaque_ GET3 ( ortholog_one2one ) Mouse_ Get3 ( ortholog_one2one ) Pig_ GET3 ( ortholog_one2one ) Rat_ Get3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in the epithelial cells of the liver, kidney, and stomach wall, in the adrenal medulla, in the islet cells of the pancreas, in the red pulp of the spleen, and in cardiac and skeletal muscle. {ECO:0000269|PubMed:9774623}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6SO5 (EM 4.20A ) |
| DBSNP | rs8177499 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:17382883, ECO:0000269|PubMed:21444755, ECO:0000269|PubMed:9736449}. Endoplasmic reticulum {ECO:0000269|PubMed:17382883, ECO:0000269|PubMed:21444755}. Nucleus, nucleolus {ECO:0000269|PubMed:21444755, ECO:0000269|PubMed:9736449}. |
| Mouse PG classification | NA |
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