| Gene Information | |
|---|---|
| Gene Name | GENX-3414 |
| Organism | Homo sapiens (Human) |
| Gene Length | 358 |
| Protein Names | Starch-binding domain-containing protein 1 (Genethonin-1) (Glycophagy cargo receptor STBD1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O95210 |
| Gene Card | STBD1 |
| Uniprot ID | O95210 |
| Pfam | PF00686 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed at high level in skeletal and cardiac muscles. Moderately expressed in liver and placenta. No expression is found in pancreas, kidney or lung. Present in skeletal muscle, heart and placenta (at protein level). {ECO:0000269|PubMed:9794794}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.097071(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Preautophagosomal structure membrane {ECO:0000269|PubMed:20810658, ECO:0000305|PubMed:21893048}; Single-pass type III membrane protein {ECO:0000305|PubMed:9794794}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:24837458}; Single-pass type III membrane protein {ECO:0000305|PubMed:9794794}. Cell membrane, sarcolemma, T-tubule {ECO:0000269|PubMed:9794794}. Note=Also detected near the junctional sarcoplasmic reticulum (PubMed:9794794). Concentrates at perinuclear structures (PubMed:21893048). {ECO:0000269|PubMed:21893048, ECO:0000269|PubMed:9794794}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |