| Gene Information | |
|---|---|
| Gene Name | GEN1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 908 |
| Protein Names | Flap endonuclease GEN homolog 1 (EC 3.1.-.-) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000178295 ) |
| Evolutionary Stage | Euk_Archaea |
| AlphaFoldDB | Q17RS7 |
| Gene Card | GEN1 |
| Uniprot ID | Q17RS7 |
| Pfam | PF18704; PF00867; PF00752 |
| In ASD | no |
| Allosteric Prediction | no (-0.53729212) |
| Ortholog in Animals | Alpaca_ GEN1 ( ortholog_one2one ) Dog_ GEN1 ( ortholog_one2one ) GuineaPig_ GEN1 ( ortholog_one2one ) Macaque_ GEN1 ( ortholog_one2one ) Mouse_ Gen1 ( ortholog_one2one ) Pig_ GEN1 ( ortholog_one2one ) Rat_ Gen1 ( ortholog_one2one ) Rabbit_ GEN1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FEN1, EXO1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002657(Rat);0.08(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5T9J (X-ray 3.00A ) |
| DBSNP | rs1812152 rs16981869 rs10177628 rs300175 rs300169 rs17315702 |
| Subcellular location [CC] | Nucleus {ECO:0000305|PubMed:26578604, ECO:0000305|PubMed:28049850}. |
| Mouse PG classification | NA |
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