| Gene Information | |
|---|---|
| Gene Name | MAPRE2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 327 |
| Protein Names | Microtubule-associated protein RP/EB family member 2 (APC-binding protein EB2) (End-binding protein 2) (EB2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000166974 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q15555 |
| Gene Card | MAPRE2 |
| Uniprot ID | Q15555 |
| Pfam | PF00307; PF03271 |
| In ASD | no |
| Allosteric Prediction | no (-1.17502093) |
| Ortholog in Animals | Alpaca_ MAPRE2 ( ortholog_one2one ) Dog_ MAPRE2 ( ortholog_one2one ) GuineaPig_ MAPRE2 ( ortholog_one2one ) Macaque_ MAPRE2 ( ortholog_one2one ) Mouse_ Mapre2 ( ortholog_one2one ) Pig_ MAPRE2 ( ortholog_one2one ) Rat_ AABR07031491.2 ( ortholog_one2one ) Rabbit_ MAPRE2 ( ortholog_one2one ) |
| Ohnologs | MAPRE1, MAPRE3 |
| Paralogs | MAPRE3, MAPRE1 |
| Tissue | gall.bladder, spinal.cord, substantia.nigra, zone.of.skin |
| Tissue Specificity | Expressed in different tumor cell lines. Up-regulated in activated B- and T-lymphocytes. {ECO:0000269|PubMed:9233623}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.017647(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs864309719 rs864309717 rs864309720 rs11538993 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:10188731}. Note=Associated with the microtubule network. Accumulates at the plus end of microtubules. |
| Mouse PG classification | NA |
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