| Gene Information | |
|---|---|
| Gene Name | GCAP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 201 |
| Protein Names | Guanylyl cyclase-activating protein 1 (GCAP 1) (Guanylate cyclase activator 1A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P43080 |
| Gene Card | GUCA1A |
| Uniprot ID | P43080 |
| Pfam | PF13499; PF13833 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | In the retina, it is expressed in rod and cone photoreceptors. {ECO:0000269|PubMed:9620085}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs104893968 rs104893967 rs771261841 rs121434631 |
| Subcellular location [CC] | Membrane; Lipid-anchor {ECO:0000250|UniProtKB:P46065}. Photoreceptor inner segment {ECO:0000269|PubMed:9620085}. Cell projection, cilium, photoreceptor outer segment {ECO:0000269|PubMed:9620085}. Note=Present at higher levels in cone than in rod outer segments (PubMed:9620085). Subcellular location is not affected by light or dark conditions. {ECO:0000269|PubMed:9620085}. |
| Mouse PG classification | NA |
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