| Gene Information | |
|---|---|
| Gene Name | PRRX1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 245 |
| Protein Names | Paired mesoderm homeobox protein 1 (Homeobox protein PHOX1) (Paired-related homeobox protein 1) (PRX-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000116132 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P54821 |
| Gene Card | PRRX1 |
| Uniprot ID | P54821 |
| Pfam | PF00046; PF03826 |
| In ASD | no |
| Allosteric Prediction | no (-1.609863241) |
| Ortholog in Animals | Alpaca_ PRRX1 ( ortholog_one2one ) Dog_ PRRX1 ( ortholog_one2one ) GuineaPig_ PRRX1 ( ortholog_one2one ) Macaque_ PRRX1 ( ortholog_one2one ) Mouse_ Prrx1 ( ortholog_one2one ) Pig_ PRRX1 ( ortholog_one2one ) Rat_ Prrx1 ( ortholog_one2one ) Rabbit_ PRRX1 ( ortholog_one2one ) |
| Ohnologs | PRRX2, SHOX2 |
| Paralogs | ARGFX, PAX7, PAX3, ALX4, PAX2, UNCX, RAX2, PAX8, DMBX1, DPRX, PAX5, ISX, ALX3, RHOXF2B, RHOXF2, GSC2, SEBOX, RAX, DRGX, ARX, RHOXF1, PITX3, SHOX, SHOX2, PRRX2, OTX2, PAX4, EVX1, PAX1, PITX2, PHOX2A, CRX, PHOX2B, EVX2, ALX1, VSX2, MIXL1, DUXA, PAX6, OTP, HESX1, NOBOX, PROP1, PAX9, GSC, ESX1, DUXB, DUX4, PITX1, OTX1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs387906667 |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | HPG |
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