| Gene Information | |
|---|---|
| Gene Name | TMPRSS11B |
| Organism | Homo sapiens (Human) |
| Gene Length | 416 |
| Protein Names | Transmembrane protease serine 11B (EC 3.4.21.-) (Airway trypsin-like protease 5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000185873 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q86T26 |
| Gene Card | TMPRSS11B |
| Uniprot ID | Q86T26 |
| Pfam | PF01390; PF00089 |
| In ASD | no |
| Allosteric Prediction | no (-0.98428029) |
| Ortholog in Animals | Alpaca_ TMPRSS11B ( ortholog_one2one ) Macaque_ TMPRSS11B ( ortholog_one2one ) Pig_ TMPRSS11B ( ortholog_one2one ) Rabbit_ TMPRSS11B ( ortholog_one2one ) |
| Ohnologs | PRSS22, ACR, TMPRSS4, TMPRSS5, PRSS27 |
| Paralogs | TMPRSS15, TMPRSS6, HPN, TMPRSS11E, ST14, TMPRSS3, TMPRSS13, TMPRSS11D, TMPRSS2, PRSS22, TMPRSS11A, TMPRSS7, TMPRSS9, TMPRSS5, PRSS21, PRSS41, TMPRSS11F |
| Tissue | esophagus, tongue, esophagus.mucosa |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12331141 rs2319796 rs2319797 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:24498351}; Single-pass type II membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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