Gene Information
Gene NameGDPD3
OrganismHomo sapiens (Human)
Gene Length318
Protein NamesLysophospholipase D GDPD3 (EC 3.1.4.-) (Glycerophosphodiester phosphodiesterase 7) (Glycerophosphodiester phosphodiesterase domain-containing protein 3)
Target NameNA
Target TypeNA
Gene Age950 ( ENSG00000102886 )
Evolutionary StageEuk+Bac
AlphaFoldDBQ7L5L3
Gene CardGDPD3
Uniprot IDQ7L5L3
PfamPF03009
In ASDno
Allosteric Predictionno (-0.739171058)
Ortholog in AnimalsAlpaca_ GDPD3 ( ortholog_one2one )
Dog_ GDPD3 ( ortholog_one2one )
GuineaPig_ GDPD3 ( ortholog_one2one )
Macaque_ GDPD3 ( ortholog_one2one )
Mouse_ Gdpd3 ( ortholog_one2one )
Pig_ GDPD3 ( ortholog_one2one )
Rat_ Gdpd3 ( ortholog_one2one )
Rabbit_ GDPD3 ( ortholog_one2one )
OhnologsGDPD1
ParalogsGDPD4, GDPD2, GDPD1, GDE1, GDPD5
Tissuecolon, tongue
Tissue SpecificityWidely expressed, with high level in kidney and ovary. {ECO:0000269|PubMed:27637550}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Membrane {ECO:0000250|UniProtKB:Q99LY2};
Multi-pass membrane protein {ECO:0000250|UniProtKB:Q99LY2}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q99LY2}. Endoplasmic reticulum {ECO:0000269|PubMed:27637550}. Note=Partially co-localized with CANX. {ECO:0000250|UniProtKB:Q99LY2}.
Mouse PG classificationNA
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