| Gene Information | |
|---|---|
| Gene Name | GDPD1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 314 |
| Protein Names | Lysophospholipase D GDPD1 (EC 3.1.4.-) (Glycerophosphodiester phosphodiesterase 4) (Glycerophosphodiester phosphodiesterase domain-containing protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000153982 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q8N9F7 |
| Gene Card | GDPD1 |
| Uniprot ID | Q8N9F7 |
| Pfam | PF03009 |
| In ASD | no |
| Allosteric Prediction | no (-0.577349256) |
| Ortholog in Animals | Alpaca_ GDPD1 ( ortholog_one2one ) Dog_ GDPD1 ( ortholog_one2one ) GuineaPig_ GDPD1 ( ortholog_one2one ) Macaque_ GDPD1 ( ortholog_one2one ) Mouse_ Gdpd1 ( ortholog_one2one ) Rat_ Gdpd1 ( ortholog_one2one ) Rabbit_ GDPD1 ( ortholog_one2one ) |
| Ohnologs | GDPD3 |
| Paralogs | GDPD4, GDPD2, GDE1, GDPD5, GDPD3 |
| Tissue | NA |
| Tissue Specificity | Widely expressed with high expression level in testis. {ECO:0000269|PubMed:16147865, ECO:0000269|PubMed:27637550}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:18991142}. Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:18991142}. Endoplasmic reticulum {ECO:0000269|PubMed:27637550}. Note=Concentrated at the perinuclear region and the cell periphery (PubMed:18991142). {ECO:0000269|PubMed:18991142}. |
| Mouse PG classification | NA |
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