| Gene Information | |
|---|---|
| Gene Name | GDF9 |
| Organism | Homo sapiens (Human) |
| Gene Length | 454 |
| Protein Names | Growth/differentiation factor 9 (GDF-9) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000164404 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O60383 |
| Gene Card | GDF9 |
| Uniprot ID | O60383 |
| Pfam | PF00019 |
| In ASD | no |
| Allosteric Prediction | no (-0.336866673) |
| Ortholog in Animals | Alpaca_ GDF9 ( ortholog_one2one ) Alpaca_ GDF9 ( ortholog_one2many ) Dog_ GDF9 ( ortholog_one2one ) GuineaPig_ GDF9 ( ortholog_one2one ) Macaque_ GDF9 ( ortholog_one2one ) Mouse_ Gdf9 ( ortholog_one2one ) Pig_ GDF9 ( ortholog_one2one ) Rat_ Gdf9 ( ortholog_one2one ) Rabbit_ GDF9 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | BMP3, MSTN, INHBC, GDF15, BMP6, INHBA, GDF6, TGFB3, BMP2, BMP10, TGFB1, INHA, GDF11, BMP5, BMP7, INHBB, GDF5, GDF1, GDF2, BMP4, LEFTY1, LEFTY2, GDF3, INHBE, GDF7, GDF10, BMP15, TGFB2, BMP8A, BMP8B, NODAL |
| Tissue | NA |
| Tissue Specificity | Expressed in ovarian granulosa cells. Present in oocytes of primary follicles (at protein level). {ECO:0000269|PubMed:10443672, ECO:0000269|PubMed:12050262}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs138136756 rs61754583 rs149821575 rs76349024 rs1205723048 rs373477788 rs118080183 rs61754582 |
| Subcellular location [CC] | Secreted {ECO:0000250}. |
| Mouse PG classification | NA |
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