| Gene Information | |
|---|---|
| Gene Name | GDF3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 364 |
| Protein Names | Growth/differentiation factor 3 (GDF-3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000184344 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9NR23 |
| Gene Card | GDF3 |
| Uniprot ID | Q9NR23 |
| Pfam | PF00019 |
| In ASD | no |
| Allosteric Prediction | no (-1.362834448) |
| Ortholog in Animals | Alpaca_ GDF3 ( ortholog_one2one ) Dog_ GDF3 ( ortholog_one2one ) Macaque_ GDF3 ( ortholog_one2one ) Mouse_ Gdf3 ( ortholog_one2one ) Pig_ GDF3 ( ortholog_one2one ) Rat_ Gdf3 ( ortholog_one2one ) Rabbit_ GDF3 ( ortholog_one2one ) |
| Ohnologs | BMP6 |
| Paralogs | BMP3, MSTN, INHBC, GDF15, BMP6, INHBA, GDF6, TGFB3, BMP2, BMP10, TGFB1, INHA, GDF9, GDF11, BMP5, BMP7, INHBB, GDF5, GDF1, GDF2, BMP4, LEFTY1, LEFTY2, INHBE, GDF7, GDF10, BMP15, TGFB2, BMP8A, BMP8B, NODAL |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs146973734 rs12819884 rs140926412 rs387906946 rs387906945 rs2302516 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:19864492, ECO:0000269|PubMed:21805089}. Cytoplasm {ECO:0000269|PubMed:19864492, ECO:0000269|PubMed:21805089}. Note=Mainly accumulated in the cytoplasm. {ECO:0000269|PubMed:21805089}. |
| Mouse PG classification | LPG |
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