| Gene Information | |
|---|---|
| Gene Name | GDE |
| Organism | Homo sapiens (Human) |
| Gene Length | 1532 |
| Protein Names | Glycogen debranching enzyme (Glycogen debrancher) [Includes: 4-alpha-glucanotransferase (EC 2.4.1.25) (Oligo-1,4-1,4-glucantransferase); Amylo-alpha-1,6-glucosidase (Amylo-1,6-glucosidase) (EC 3.2.1.33) (Dextrin 6-alpha-D-glucosidase)] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P35573 |
| Gene Card | AGL |
| Uniprot ID | P35573 |
| Pfam | PF06202; PF14701; PF14702; PF14699 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Liver, kidney and lymphoblastoid cells express predominantly isoform 1; whereas muscle and heart express not only isoform 1, but also muscle-specific isoform mRNAs (isoforms 2, 3 and 4). Isoforms 5 and 6 are present in both liver and muscle. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35278779 rs17121403 rs17121464 rs3736297 rs34714252 rs3753494 rs2230307 rs2230308 rs11807956 rs12043139 rs112795811 rs118203964 rs12118058 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:17908927}. Note=Under glycogenolytic conditions localizes to the nucleus. |
| Mouse PG classification | NA |
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