| Gene Information | |
|---|---|
| Gene Name | TCF3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 654 |
| Protein Names | Transcription factor E2-alpha (Class B basic helix-loop-helix protein 21) (bHLHb21) (Immunoglobulin enhancer-binding factor E12/E47) (Immunoglobulin transcription factor 1) (Kappa-E2-binding factor) (Transcription factor 3) (TCF-3) (Transcription factor ITF-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000071564 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P15923 |
| Gene Card | TCF3 |
| Uniprot ID | P15923 |
| Pfam | PF00010 |
| In ASD | no |
| Allosteric Prediction | no (-0.538158599) |
| Ortholog in Animals | Alpaca_ TCF3 ( ortholog_one2one ) Dog_ TCF3 ( ortholog_one2one ) GuineaPig_ TCF3 ( ortholog_one2one ) Macaque_ TCF3 ( ortholog_one2one ) Mouse_ Tcf3 ( ortholog_one2one ) Pig_ TCF3 ( ortholog_one2one ) Rat_ Tcf3 ( ortholog_one2one ) |
| Ohnologs | TCF12, TCF4 |
| Paralogs | TCF4, TCF12 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2MH0 (NMR - ) 2YPA (X-ray 2.80A ) 2YPB (X-ray 2.87A ) 3U5V (X-ray 1.70A ) 6MGN (X-ray 1.90A ) |
| DBSNP | rs376780559 rs35354874 rs11879402 rs1052692 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:31696227}. |
| Mouse PG classification | NA |
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