| Gene Information | |
|---|---|
| Gene Name | NMUR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 426 |
| Protein Names | Neuromedin-U receptor 1 (NMU-R1) (G-protein coupled receptor 66) (G-protein coupled receptor FM-3) |
| Target Name | neuromedin-u receptor 1 |
| Target Type | Literature-reported target |
| Gene Age | 645 ( ENSG00000171596 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9HB89 |
| Gene Card | NMUR1 |
| Uniprot ID | Q9HB89 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | yes (1.335362635) |
| Ortholog in Animals | Alpaca_ NMUR1 ( ortholog_one2one ) Dog_ NMUR1 ( ortholog_one2one ) Macaque_ NMUR1 ( ortholog_one2one ) Mouse_ Nmur1 ( ortholog_one2one ) Pig_ NMUR1 ( ortholog_one2one ) Rat_ Nmur1 ( ortholog_one2one ) Rabbit_ NMUR1 ( ortholog_one2one ) |
| Ohnologs | NTSR1, MLNR, GHSR |
| Paralogs | BRS3, NMBR, EDNRA, GRPR, EDNRB, GPR37, TRHR, GPR148, GPR37L1, NMUR2, NTSR1, GHSR, NTSR2, GPR39, MLNR |
| Tissue | NA |
| Tissue Specificity | Expressed in greatest abundance in peripheral organs, particularly in elements of the gastrointestinal and urogenital systems with highest levels in testes. In central nervous system structures express levels are much lower than those seen in peripheral organs. Within the CNS, has been detected in highest abundance in the cerebellum, dorsal root ganglia, hippocampus, and spinal cord. {ECO:0000269|PubMed:10899166, ECO:0000269|PubMed:9782091}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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