Gene Information
Gene NameHILPDA
OrganismHomo sapiens (Human)
Gene Length63
Protein NamesHypoxia-inducible lipid droplet-associated protein (Hypoxia-inducible gene 2 protein)
Target NameNA
Target TypeNA
Gene Age132 ( ENSG00000135245 )
Evolutionary StageMammalia
AlphaFoldDBQ9Y5L2
Gene CardHILPDA
Uniprot IDQ9Y5L2
PfamPF15220
In ASDno
Allosteric Predictionno (-1.47104906)
Ortholog in AnimalsAlpaca_ HILPDA ( ortholog_one2one )
GuineaPig_ HILPDA ( ortholog_one2one )
Mouse_ Hilpda ( ortholog_one2one )
Rabbit_ HILPDA ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityHighly expressed in renal cell carcinoma cells but barely detectable in adjacent normal kidney tissue. Detected in some cervical and endometrial cancers. Expression also detected in fetal kidney with little or no expression observed in normal adult heart, liver, lung, pancreas, prostate or spinal cord (at protein level). {ECO:0000269|PubMed:15930302, ECO:0000269|PubMed:20624928, ECO:0000269|PubMed:21614900}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Lipid droplet. Secreted. Membrane {ECO:0000305};
Single-pass membrane protein {ECO:0000305}.
Mouse PG classificationNA
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