| Gene Information | |
|---|---|
| Gene Name | GCPL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 335 |
| Protein Names | tRNA N6-adenosine threonylcarbamoyltransferase (EC 2.3.1.234) (N6-L-threonylcarbamoyladenine synthase) (t(6)A synthase) (O-sialoglycoprotein endopeptidase) (hOSGEP) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEP) (tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9NPF4 |
| Gene Card | OSGEP |
| Uniprot ID | Q9NPF4 |
| Pfam | PF00814 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed at low level. Expressed in heart, placenta, liver, kidney, lung, brain, skeletal muscle and pancreas. {ECO:0000269|PubMed:12039036}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.012719(Mouse);0.002590(Rat);0.036364(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6GWJ (X-ray 1.95A ) |
| DBSNP | rs1555331969 rs200347983 rs140583554 rs140076803 rs1443735811 rs1334263407 rs778931753 rs773173317 rs374322839 rs144732839 rs144732839 rs753237335 rs761839638 |
| Subcellular location [CC] | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03180, ECO:0000269|PubMed:28805828}. Nucleus {ECO:0000255|HAMAP-Rule:MF_03180, ECO:0000269|PubMed:22912744, ECO:0000269|PubMed:28805828}. |
| Mouse PG classification | NA |
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