Gene Information
Gene NameCLEC16A
OrganismHomo sapiens (Human)
Gene Length1053
Protein NamesProtein CLEC16A (C-type lectin domain family 16 member A)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000038532 )
Evolutionary StageEukaryota
AlphaFoldDBQ2KHT3
Gene CardCLEC16A
Uniprot IDQ2KHT3
PfamPF19439; PF09758
In ASDno
Allosteric Predictionno (-0.500090829)
Ortholog in AnimalsAlpaca_ CLEC16A ( ortholog_one2one )
Dog_ CLEC16A ( ortholog_one2one )
GuineaPig_ CLEC16A ( ortholog_one2one )
Macaque_ CLEC16A ( ortholog_one2one )
Mouse_ Clec16a ( ortholog_one2one )
Pig_ CLEC16A ( ortholog_one2one )
Rat_ Clec16a ( ortholog_one2one )
Rabbit_ CLEC16A ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityAlmost exclusively expressed in immune cells, including dendritic cells, B-lymphocytes and natural killer cells. {ECO:0000269|PubMed:17632545}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs2241100 
Subcellular location [CC]Endosome membrane {ECO:0000250|UniProtKB:Q80U30};
Peripheral membrane protein {ECO:0000250|UniProtKB:Q80U30}. Lysosome membrane {ECO:0000250|UniProtKB:Q80U30};
Peripheral membrane protein {ECO:0000250|UniProtKB:Q80U30}. Note=Associates with the endolysosome membrane. {ECO:0000250|UniProtKB:Q80U30}.
Mouse PG classificationNA
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