| Gene Information | |
|---|---|
| Gene Name | KIF18A |
| Organism | Homo sapiens (Human) |
| Gene Length | 898 |
| Protein Names | Kinesin-like protein KIF18A (Marrow stromal KIF18A) (MS-KIF18A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000121621 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8NI77 |
| Gene Card | KIF18A |
| Uniprot ID | Q8NI77 |
| Pfam | PF00225 |
| In ASD | yes |
| Allosteric Prediction | yes (0.789452162) |
| Ortholog in Animals | Alpaca_ KIF18A ( ortholog_one2one ) Dog_ KIF18A ( ortholog_one2one ) GuineaPig_ KIF18A ( ortholog_one2one ) Macaque_ KIF18A ( ortholog_one2one ) Mouse_ Kif18a ( ortholog_one2one ) Pig_ KIF18A ( ortholog_one2one ) Rat_ Kif18a ( ortholog_one2one ) Rabbit_ KIF18A ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | KIF27, KIF1C, KIF26B, KIF2B, KIF13A, KIFC3, KIFC2, KIF16B, KIF4A, KIF2A, KIF20A, KIF22, KIF3A, KIF13B, KIF5B, KIF1A, KIF3B, KIF3C, KIF1B, CENPE, KIF26A, KIF23, KIF7, KIF5A, KIF18B, KIF25, KIF9, KIF6, KIF14, KIF21B, KIF11, KIF15, KIFC1, KIF12, KIF4B, KIF24, KIF2C, KIF21A, KIF19, KIF17, KIF5C |
| Tissue | testis |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.022222(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3LRE (X-ray 2.20A ) 5OAM (EM 5.50A ) 5OCU (EM 5.20A ) 5OGC (EM 4.80A ) 7RSI (EM 4.90A ) |
| DBSNP | rs12272419 rs34913484 rs10458896 |
| Subcellular location [CC] | Cell projection, ruffle. Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. |
| Mouse PG classification | NA |
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