| Gene Information | |
|---|---|
| Gene Name | GCNT2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 402 |
| Protein Names | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase (N-acetylglucosaminyltransferase) (EC 2.4.1.150) (I-branching enzyme) (IGNT) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000111846 ) 3 ( ENSG00000285222 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8N0V5 |
| Gene Card | GCNT2 |
| Uniprot ID | Q8N0V5 |
| Pfam | PF02485 |
| In ASD | no |
| Allosteric Prediction | no (-1.256257323) |
| Ortholog in Animals | Alpaca_ GCNT2 ( ortholog_one2one ) Dog_ GCNT2 ( ortholog_one2one ) GuineaPig_ GCNT2 ( ortholog_one2one ) Macaque_ GCNT2 ( ortholog_one2one ) Mouse_ Gcnt2 ( ortholog_one2one ) Pig_ GCNT2 ( ortholog_one2one ) Rat_ Gcnt2 ( ortholog_one2one ) |
| Ohnologs | GCNT7 |
| Paralogs | WSCD1, GCNT7, XYLT1, GCNT3, GCNT1, GCNT4, XYLT2, WSCD2 |
| Tissue | NA |
| Tissue Specificity | [Isoform B]: Expressed in lens epithelium cells. {ECO:0000269|PubMed:12424189}.; [Isoform C]: Expressed in reticulocytes. {ECO:0000269|PubMed:12468428}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs137853339 rs137853340 rs56141211 rs55940927 |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
| Mouse PG classification | LPG |
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