| Gene Information | |
|---|---|
| Gene Name | MRC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1456 |
| Protein Names | Macrophage mannose receptor 1 (MMR) (C-type lectin domain family 13 member D) (C-type lectin domain family 13 member D-like) (Human mannose receptor) (hMR) (Macrophage mannose receptor 1-like protein 1) (CD antigen CD206) |
| Target Name | macrophage mannose receptor 1 |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000260314 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P22897 |
| Gene Card | MRC1 |
| Uniprot ID | P22897 |
| Pfam | PF00040; PF00059; PF00652 |
| In ASD | no |
| Allosteric Prediction | yes (0.439608861) |
| Ortholog in Animals | Alpaca_ MRC1 ( ortholog_one2one ) Dog_ MRC1 ( ortholog_one2one ) GuineaPig_ MRC1 ( ortholog_one2one ) Macaque_ MRC1 ( ortholog_one2one ) Mouse_ Mrc1 ( ortholog_one2one ) Pig_ MRC1 ( ortholog_one2one ) Rat_ Mrc1 ( ortholog_one2one ) Rabbit_ MRC1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | LY75, PLA2R1, MRC2, CD302 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);NULL(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1EGG (X-ray 2.30A ) 1EGI (X-ray 2.30A ) 5XTS (X-ray 2.00A ) 5XTW (X-ray 3.20A ) 6INN (X-ray 3.00A ) 6INO (X-ray 3.05A ) 6INU (X-ray 2.65A ) 6INV (X-ray 3.30A ) 6IOE (X-ray 2.90A ) 7JUB (X-ray 1.20A ) 7JUC (X-ray 1.40A ) 7JUD (X-ray 1.40A ) 7JUE (X-ray 1.40A ) 7JUF (X-ray 1.40A ) 7JUG (X-ray 1.40A ) 7JUH (X-ray 1.40A ) 7L61 (X-ray 1.35A ) 7L62 (X-ray 1.55A ) 7L63 (X-ray 1.65A ) 7L64 (X-ray 1.35A ) 7L65 (X-ray 1.35A ) 7L66 (X-ray 1.75A ) 7L67 (X-ray 1.20A ) 7L68 (X-ray 1.40A ) |
| DBSNP | rs2296414 rs606231248 rs71497223 rs71497225 |
| Subcellular location [CC] | Endosome membrane {ECO:0000269|PubMed:20035344}; Single-pass type I membrane protein {ECO:0000269|PubMed:20035344}. Cell membrane {ECO:0000269|PubMed:20035344}; Single-pass type I membrane protein {ECO:0000269|PubMed:20035344}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |