| Gene Information | |
|---|---|
| Gene Name | GPR45 |
| Organism | Homo sapiens (Human) |
| Gene Length | 372 |
| Protein Names | Probable G-protein coupled receptor 45 (PSP24-1) (PSP24-alpha) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000135973 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9Y5Y3 |
| Gene Card | GPR45 |
| Uniprot ID | Q9Y5Y3 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | yes (0.592391989) |
| Ortholog in Animals | Dog_ GPR45 ( ortholog_one2one ) GuineaPig_ GPR45 ( ortholog_one2one ) Macaque_ GPR45 ( ortholog_one2one ) Mouse_ Gpr45 ( ortholog_one2one ) Pig_ GPR45 ( ortholog_one2one ) Rat_ Gpr45 ( ortholog_one2one ) |
| Ohnologs | GPR63 |
| Paralogs | GPR63, GPR78, GPR26 |
| Tissue | NA |
| Tissue Specificity | Expressed in brain; detected in the basal forebrain, frontal cortex, and caudate, but not in thalamus, hippocampus, or putamen. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35946826 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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