| Gene Information | |
|---|---|
| Gene Name | CHST15 |
| Organism | Homo sapiens (Human) |
| Gene Length | 561 |
| Protein Names | Carbohydrate sulfotransferase 15 (EC 2.8.2.33) (B-cell RAG-associated gene protein) (hBRAG) (N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase) (GalNAc4S-6ST) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000182022 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q7LFX5 |
| Gene Card | CHST15 |
| Uniprot ID | Q7LFX5 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.339083478) |
| Ortholog in Animals | Alpaca_ CHST15 ( ortholog_one2one ) GuineaPig_ CHST15 ( ortholog_one2one ) Macaque_ CHST15 ( ortholog_one2one ) Mouse_ Chst15 ( ortholog_one2one ) Pig_ CHST15 ( ortholog_one2one ) Rat_ Chst15 ( ortholog_one2one ) Rabbit_ CHST15 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in B-cell-enriched tissues but not in fetal or adult thymus. Expressed in fetal and adult spleen, lymph node, tonsil, bone marrow and peripheral leukocytes. Not expressed in T-cells. In pro-B, pre-B, and mature B-cell lines, it colocalizes with RAG1. {ECO:0000269|PubMed:9754571}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000305|PubMed:10749872}; Single-pass type II membrane protein {ECO:0000305|PubMed:10749872}. Note=A small fraction may also be present at the cell surface, where it acts as a B-cell receptor. |
| Mouse PG classification | NA |
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