| Gene Information | |
|---|---|
| Gene Name | GCL |
| Organism | Homo sapiens (Human) |
| Gene Length | 217 |
| Protein Names | Grancalcin |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P28676 |
| Gene Card | GCA |
| Uniprot ID | P28676 |
| Pfam | PF13833 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Detected in neutrophils and macrophages (at protein level). Highly expressed in bone marrow. {ECO:0000269|PubMed:1737748}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1F4O (X-ray 2.50A ) 1F4Q (X-ray 1.90A ) 1K94 (X-ray 1.70A ) 1K95 (X-ray 1.90A ) |
| DBSNP | rs17783344 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:1530588, ECO:0000269|PubMed:1737748}. Cytoplasmic granule membrane {ECO:0000269|PubMed:1737748, ECO:0000305|PubMed:1530588}; Peripheral membrane protein; Cytoplasmic side. Note=Primarily cytosolic in the absence of calcium or magnesium ions. Relocates to granules and other membranes in response to elevated calcium and magnesium levels. {ECO:0000269|PubMed:1737748}. |
| Mouse PG classification | NA |
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