Gene Information
Gene NameGCDH
OrganismHomo sapiens (Human)
Gene Length438
Protein NamesGlutaryl-CoA dehydrogenase, mitochondrial (GCD) (EC 1.3.8.6)
Target Nameglutaryl-coa dehydrogenase, mitochondrial
Target TypeNA
Gene Age1064 ( ENSG00000105607 )
Evolutionary StageCellular_organisms
AlphaFoldDBQ92947
Gene CardGCDH
Uniprot IDQ92947
PfamPF00441; PF02770; PF02771
In ASDno
Allosteric Predictionyes (0.434283298)
Ortholog in AnimalsAlpaca_ GCDH ( ortholog_one2one )
Dog_ GCDH ( ortholog_one2one )
GuineaPig_ GCDH ( ortholog_one2one )
Macaque_ GCDH ( ortholog_one2one )
Mouse_ Gcdh ( ortholog_one2one )
Pig_ GCDH ( ortholog_one2one )
Rat_ Gcdh ( ortholog_one2one )
Rabbit_ GCDH ( ortholog_one2one )
OhnologsNA
ParalogsACOX1, ACAD11, ACADM, ACAD9, IVD, ACOXL, ACAD10, ACADS, ACOX3, ACAD8, ACOX2, ACADVL, ACADSB, ACADL
TissueNA
Tissue SpecificityIsoform Long and isoform Short are expressed in fibroblasts and liver.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1SIQ  (X-ray  2.10A  )  1SIR  (X-ray  2.60A  )  2R0M  (X-ray  2.70A  )  2R0N  (X-ray  2.30A  ) 
DBSNP rs1555749239  rs142967670  rs566417795  rs1273164833  rs776758971  rs766325846  rs897036690  rs139851890  rs1003611285  rs777201305  rs749452002  rs774526353  rs149120354  rs121434373  rs747920711  rs751583656  rs766518430  rs745357523  rs765723076  rs751742575  rs121434371  rs121434366  rs761765983  rs764993096  rs1260580183  rs1205368991  rs1247712895  rs779315456  rs794726972  rs1257292639  rs768925619  rs781477694  rs748275416  rs121434370  rs1348974766  rs567564095  rs150938052  rs764608975  rs398123190  rs778153326  rs372983141  rs1282266790  rs121434372  rs786204626  rs121434369  rs1555751379  rs147611168  rs121434368  rs151201155  rs121434367  rs745360675  rs933624223 
Subcellular location [CC]Mitochondrion matrix.
Mouse PG classificationHPG
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