Gene Information
Gene NameGCC2
OrganismHomo sapiens (Human)
Gene Length1684
Protein NamesGRIP and coiled-coil domain-containing protein 2 (185 kDa Golgi coiled-coil protein) (GCC185) (CLL-associated antigen KW-11) (CTCL tumor antigen se1-1) (Ran-binding protein 2-like 4) (RanBP2L4) (Renal carcinoma antigen NY-REN-53)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000135968 )
Evolutionary StageEumetazoa
AlphaFoldDBQ8IWJ2
Gene CardGCC2
Uniprot IDQ8IWJ2
PfamPF01465; PF16704
In ASDno
Allosteric Predictionno (-0.888191359)
Ortholog in AnimalsAlpaca_ GCC2 ( ortholog_one2one )
Dog_ GCC2 ( ortholog_one2one )
Macaque_ GCC2 ( ortholog_one2one )
Mouse_ Gcc2 ( ortholog_one2one )
Pig_ GCC2 ( ortholog_one2one )
Rat_ Gcc2 ( ortholog_one2one )
Rabbit_ GCC2 ( ortholog_one2one )
OhnologsCEP250
ParalogsNUMA1, GOLGA3, CEP164
TissueNA
Tissue SpecificityUbiquitous. {ECO:0000269|PubMed:11149944}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.015385(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 3BBP  (X-ray  3.00A 
DBSNP rs2718698  rs1061202 
Subcellular location [CC]Cytoplasm. Golgi apparatus, trans-Golgi network membrane;
Peripheral membrane protein.
Mouse PG classificationNA
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