| Gene Information | |
|---|---|
| Gene Name | NDN |
| Organism | Homo sapiens (Human) |
| Gene Length | 321 |
| Protein Names | Necdin |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000182636 ) 3 ( ENSG00000288364 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q99608 |
| Gene Card | NDN |
| Uniprot ID | Q99608 |
| Pfam | PF01454 |
| In ASD | no |
| Allosteric Prediction | no (-0.712829785) |
| Ortholog in Animals | Dog_ NDN ( ortholog_one2one ) Macaque_ NDN ( ortholog_one2one ) Mouse_ Ndn ( ortholog_one2one ) Pig_ NDN ( ortholog_one2one ) Rat_ Ndn ( ortholog_one2one ) Rabbit_ NDN ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MAGED4, MAGED4B, MAGEB17, MAGEB1, MAGEA3, MAGEA6, MAGEL2, MAGEA2, MAGEA2B, MAGEA12, MAGEB6, MAGEB6B, MAGEB2, MAGEH1, MAGEA8, MAGEE2, MAGEA11, MAGEB5, MAGED1, MAGEB10, MAGEA10, MAGEA4, TRO, MAGEB4, MAGEC3, MAGEE1, MAGEA9, MAGEA9B, MAGEB3, MAGEC1, MAGEC2, NSMCE3, MAGEA1, MAGEB18, MAGEB16, MAGEF1, MAGED2 |
| Tissue | NA |
| Tissue Specificity | Almost ubiquitous. Detected in fetal brain, lung, liver and kidney; in adult heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine and colon. Not detected in peripheral blood leukocytes. In brain, restricted to post-mitotic neurons. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs114077338 |
| Subcellular location [CC] | Perikaryon. Nucleus. Note=Neural perikarya, translocates to the nucleus of postmitotic neurons and interacts with the nuclear matrix. |
| Mouse PG classification | NA |
| click here to return to the previous page | |