| Gene Information | |
|---|---|
| Gene Name | PON |
| Organism | Homo sapiens (Human) |
| Gene Length | 355 |
| Protein Names | Serum paraoxonase/arylesterase 1 (PON 1) (EC 3.1.1.2) (EC 3.1.1.81) (EC 3.1.8.1) (Aromatic esterase 1) (A-esterase 1) (K-45) (Serum aryldialkylphosphatase 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P27169 |
| Gene Card | PON1 |
| Uniprot ID | P27169 |
| Pfam | PF01731 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Plasma, associated with HDL (at protein level). Expressed in liver, but not in heart, brain, placenta, lung, skeletal muscle, kidney or pancreas. {ECO:0000269|PubMed:8292612, ECO:0000269|PubMed:8382160}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1V04 (X-ray 2.20A ) |
| DBSNP | rs854560 rs72552787 rs13306698 rs662 |
| Subcellular location [CC] | Secreted, extracellular space. |
| Mouse PG classification | NA |
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