| Gene Information | |
|---|---|
| Gene Name | THPO |
| Organism | Homo sapiens (Human) |
| Gene Length | 353 |
| Protein Names | Thrombopoietin (C-mpl ligand) (ML) (Megakaryocyte colony-stimulating factor) (Megakaryocyte growth and development factor) (MGDF) (Myeloproliferative leukemia virus oncogene ligand) |
| Target Name | thrombopoietin |
| Target Type | Clinical trial target |
| Gene Age | 1064 ( ENSG00000090534 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P40225 |
| Gene Card | THPO |
| Uniprot ID | P40225 |
| Pfam | PF00758 |
| In ASD | no |
| Allosteric Prediction | no (-0.10917229) |
| Ortholog in Animals | Alpaca_ THPO ( ortholog_one2one ) Dog_ THPO ( ortholog_one2one ) Macaque_ THPO ( ortholog_one2one ) Mouse_ Thpo ( ortholog_one2one ) Pig_ THPO ( ortholog_one2one ) Rat_ Thpol1 ( ortholog_one2one ) Rabbit_ THPO ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | liver |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1V7M (X-ray 2.51A ) 1V7N (X-ray 3.30A ) |
| DBSNP | rs1042346 rs1126665 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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