| Gene Information | |
|---|---|
| Gene Name | TPRN |
| Organism | Homo sapiens (Human) |
| Gene Length | 711 |
| Protein Names | Taperin |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000176058 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q4KMQ1 |
| Gene Card | TPRN |
| Uniprot ID | Q4KMQ1 |
| Pfam | PF13914; PF13916 |
| In ASD | no |
| Allosteric Prediction | no (-0.657760502) |
| Ortholog in Animals | Alpaca_ TPRN ( ortholog_one2one ) Dog_ ANAPC2 ( ortholog_one2one ) GuineaPig_ TPRN ( ortholog_one2one ) Macaque_ TPRN ( ortholog_one2one ) Mouse_ Tprn ( ortholog_one2one ) Rat_ Tprn ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PPP1R18 |
| Tissue | NA |
| Tissue Specificity | Expression is detected in fetal cochlea. {ECO:0000269|PubMed:20170898}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);0.004323(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6Y9Q (X-ray 1.31A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell projection, stereocilium {ECO:0000250}. Note=Localized prominently at the taper regions of hair cell stereocilia. {ECO:0000250}. |
| Mouse PG classification | HPG |
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