| Gene Information | |
|---|---|
| Gene Name | CXCL2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 107 |
| Protein Names | C-X-C motif chemokine 2 (Growth-regulated protein beta) (Gro-beta) (Macrophage inflammatory protein 2-alpha) (MIP2-alpha) [Cleaved into: GRO-beta(5-73) (GRO-beta-T) (Hematopoietic synergistic factor) (HSF) (SB-251353)] |
| Target Name | c-x-c motif chemokine 2 |
| Target Type | Clinical trial target |
| Gene Age | 70 ( ENSG00000081041 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P19875 |
| Gene Card | CXCL2 |
| Uniprot ID | P19875 |
| Pfam | PF00048 |
| In ASD | no |
| Allosteric Prediction | no (-0.912007704) |
| Ortholog in Animals | Alpaca_ CXCL2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CXCL3, CXCL8, CXCL5, CXCL10, CXCL9, CXCL1, CXCL13, CXCL11, CXCL6, PF4, PF4V1, PPBP |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1QNK (NMR - ) 5OB5 (X-ray 1.65A ) |
| DBSNP | NA |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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