| Gene Information | |
|---|---|
| Gene Name | GATA6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 595 |
| Protein Names | Transcription factor GATA-6 (GATA-binding factor 6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000141448 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q92908 |
| Gene Card | GATA6 |
| Uniprot ID | Q92908 |
| Pfam | PF00320; PF05349 |
| In ASD | no |
| Allosteric Prediction | no (-0.231434209) |
| Ortholog in Animals | Alpaca_ GATA6 ( ortholog_one2one ) Dog_ GATA6 ( ortholog_one2one ) GuineaPig_ GATA6 ( ortholog_one2one ) Macaque_ GATA6 ( ortholog_one2one ) Mouse_ Gata6 ( ortholog_one2one ) Pig_ GATA6 ( ortholog_one2one ) Rat_ Gata6 ( ortholog_one2one ) |
| Ohnologs | GATA5, GATA4 |
| Paralogs | ZGLP1, GATA2, GATA5, TRPS1, GATA1, GATA3, GATA4 |
| Tissue | heart, left.atrium, left.ventricle, mitral.valve, ovary |
| Tissue Specificity | Expressed in heart, gut and gut-derived tissues. Expressed in skin upper pilosebaceous unit. Expression is decreased or lost in acne lesions (PubMed:33082341). {ECO:0000269|PubMed:33082341}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs116262672 rs766886560 rs1263887431 rs387906815 rs387906816 rs387906814 rs387906817 rs387906818 rs387906819 rs387906813 rs387906813 rs387906820 rs761668180 rs201707559 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:19666519, ECO:0000269|PubMed:27756709}. |
| Mouse PG classification | LPG |
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