| Gene Information | |
|---|---|
| Gene Name | GAST |
| Organism | Homo sapiens (Human) |
| Gene Length | 101 |
| Protein Names | Gastrin [Cleaved into: Gastrin-71 (Gastrin component I); Gastrin-52 (G52); Big gastrin (Gastrin component II) (Gastrin-34) (G34); Gastrin (Gastrin component III) (Gastrin-17) (G17); Gastrin-14 (G14); Gastrin-6 (G6)] |
| Target Name | gastrin |
| Target Type | Clinical trial target |
| Gene Age | 86 ( ENSG00000184502 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P01350 |
| Gene Card | GAST |
| Uniprot ID | P01350 |
| Pfam | PF00918 |
| In ASD | no |
| Allosteric Prediction | no (-0.192863009) |
| Ortholog in Animals | Alpaca_ GAST ( ortholog_one2one ) Dog_ GAST ( ortholog_one2one ) GuineaPig_ GAST ( ortholog_one2one ) Macaque_ GAST ( ortholog_one2one ) Mouse_ Gast ( ortholog_one2one ) Pig_ GAST ( ortholog_one2one ) Rat_ Gast ( ortholog_one2one ) Rabbit_ GAST ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | stomach, duodenum |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5WRJ (X-ray 2.31A ) 7F8V (EM 3.30A ) 7F8W (EM 3.10A ) 7XOW (EM 3.10A ) |
| DBSNP | rs34309618 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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