| Gene Information | |
|---|---|
| Gene Name | PDHK4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 411 |
| Protein Names | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q16654 |
| Gene Card | PDK4 |
| Uniprot ID | Q16654 |
| Pfam | PF10436; PF02518 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous; highest levels of expression in heart and skeletal muscle. {ECO:0000269|PubMed:14966024, ECO:0000269|PubMed:21816445}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2E0A (X-ray 1.86A ) 2ZDX (X-ray 2.54A ) 2ZDY (X-ray 2.40A ) 2ZKJ (X-ray 2.00A ) 3D2R (X-ray 2.03A ) 7EAT (X-ray 2.10A ) 7EBB (X-ray 1.90A ) 7EBG (X-ray 1.95A ) |
| DBSNP | rs56391840 rs55761955 rs34898343 |
| Subcellular location [CC] | Mitochondrion matrix. |
| Mouse PG classification | NA |
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