| Gene Information | |
|---|---|
| Gene Name | ASCC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 400 |
| Protein Names | Activating signal cointegrator 1 complex subunit 1 (ASC-1 complex subunit p50) (Trip4 complex subunit p50) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000138303 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8N9N2 |
| Gene Card | ASCC1 |
| Uniprot ID | Q8N9N2 |
| Pfam | PF10469; PF00013 |
| In ASD | no |
| Allosteric Prediction | no (-1.192897771) |
| Ortholog in Animals | Alpaca_ ASCC1 ( ortholog_one2one ) Dog_ ASCC1 ( ortholog_one2one ) GuineaPig_ ASCC1 ( ortholog_one2one ) Macaque_ ASCC1 ( ortholog_one2one ) Mouse_ Ascc1 ( ortholog_one2one ) Pig_ ASCC1 ( ortholog_one2one ) Rat_ Ascc1 ( ortholog_one2one ) Rabbit_ ASCC1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:12077347}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.103509(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11558719 rs146370051 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:12077347, ECO:0000269|PubMed:26924529}. Nucleus speckle {ECO:0000269|PubMed:29997253}. Note=Colocalizes with PRPF8 in nuclear speckles in the absence of DNA damage. {ECO:0000269|PubMed:29997253}. |
| Mouse PG classification | NA |
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