| Gene Information | |
|---|---|
| Gene Name | PTGER1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 402 |
| Protein Names | Prostaglandin E2 receptor EP1 subtype (PGE receptor EP1 subtype) (PGE2 receptor EP1 subtype) (Prostanoid EP1 receptor) |
| Target Name | prostaglandin e2 receptor ep1 |
| Target Type | Clinical trial target |
| Gene Age | 950 ( ENSG00000160951 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P34995 |
| Gene Card | PTGER1 |
| Uniprot ID | P34995 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | yes (1.125219814) |
| Ortholog in Animals | Alpaca_ PTGER1 ( ortholog_one2one ) GuineaPig_ PTGER1 ( ortholog_one2one ) Macaque_ PTGER1 ( ortholog_one2one ) Mouse_ Ptger1 ( ortholog_one2one ) Pig_ PTGER1 ( ortholog_one2one ) Rat_ Ptger1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TBXA2R, PTGFR, PTGER3, PTGER2, PTGDR, PTGIR, PTGER4 |
| Tissue | NA |
| Tissue Specificity | Abundant in kidney. Lower level expression in lung, skeletal muscle and spleen, lowest expression in testis and not detected in liver brain and heart. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1057362 rs28364042 rs7249305 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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