| Gene Information | |
|---|---|
| Gene Name | EXTL2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 330 |
| Protein Names | Exostosin-like 2 (EC 2.4.1.223) (Alpha-1,4-N-acetylhexosaminyltransferase EXTL2) (Alpha-GalNAcT EXTL2) (EXT-related protein 2) (Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) [Cleaved into: Processed exostosin-like 2] |
| Target Name | exostosin-like 2 |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000162694 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UBQ6 |
| Gene Card | EXTL2 |
| Uniprot ID | Q9UBQ6 |
| Pfam | PF09258 |
| In ASD | no |
| Allosteric Prediction | no (-1.238974736) |
| Ortholog in Animals | Alpaca_ EXTL2 ( ortholog_one2one ) Dog_ EXTL2 ( ortholog_one2one ) GuineaPig_ EXTL2 ( ortholog_one2one ) Macaque_ EXTL2 ( ortholog_one2one ) Mouse_ Extl2 ( ortholog_one2one ) Pig_ EXTL2 ( ortholog_one2one ) Rat_ Extl2 ( ortholog_one2one ) Rabbit_ EXTL2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | EXT1, EXTL1, EXT2, EXTL3 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.; [Processed exostosin-like 2]: Secreted. Note=A soluble form is found in the serum. |
| Mouse PG classification | NA |
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