| Gene Information | |
|---|---|
| Gene Name | GAPT |
| Organism | Homo sapiens (Human) |
| Gene Length | 157 |
| Protein Names | Protein GAPT (Growth factor receptor-bound protein 2-binding adapter protein, transmembrane) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 70 ( ENSG00000175857 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q8N292 |
| Gene Card | GAPT |
| Uniprot ID | Q8N292 |
| Pfam | PF11770 |
| In ASD | no |
| Allosteric Prediction | no (-1.436411522) |
| Ortholog in Animals | Alpaca_ GAPT ( ortholog_one2one ) Macaque_ GAPT ( ortholog_one2one ) Mouse_ Gapt ( ortholog_one2one ) Pig_ GAPT ( ortholog_one2one ) Rat_ Gapt ( ortholog_one2one ) Rabbit_ GAPT ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | substantia.nigra, zone.of.skin, lung, spleen |
| Tissue Specificity | Highly expressed in spleen and PBL, detected at lower levels in thymus, and undetectable in all other tissues tested. Also expressed in various B-cell lines, monocytic cell line THP-1 and NK-like cell line YT, but not in T-cell line Jurkat or HeLa cells. {ECO:0000269|PubMed:18559951}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35260984 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:18559951}; Single-pass membrane protein {ECO:0000269|PubMed:18559951}. |
| Mouse PG classification | NA |
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