Gene Information
Gene NameBCL2L14
OrganismHomo sapiens (Human)
Gene Length327
Protein NamesApoptosis facilitator Bcl-2-like protein 14 (Bcl2-L-14) (Apoptosis regulator Bcl-G)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000121380 )
3 ( ENSG00000281449 )
Evolutionary StageVertebrata
AlphaFoldDBQ9BZR8
Gene CardBCL2L14
Uniprot IDQ9BZR8
PfamNA
In ASDno
Allosteric Predictionno (-0.240397072)
Ortholog in AnimalsAlpaca_ BCL2L14 ( ortholog_one2one )
Dog_ BCL2L14 ( ortholog_one2one )
GuineaPig_ BCL2L14 ( ortholog_one2one )
Macaque_ BCL2L14 ( ortholog_one2one )
Mouse_ Bcl2l14 ( ortholog_one2one )
Pig_ BCL2L14 ( ortholog_one2one )
Rat_ Bcl2l14 ( ortholog_one2one )
Rabbit_ BCL2L14 ( ortholog_one2one )
OhnologsNA
ParalogsBCL2L12
Tissuesmall.intestine, testis
Tissue SpecificityIsoform 1 is widely expressed. Isoform 2 is testis-specific. {ECO:0000269|PubMed:11054413}.
Pharmacological Animal ModelsNULL(Chimpanzee);0.001000(Mouse);NULL(Rat);0.018182(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:11054413}.;
[Isoform 1]: Cytoplasm, cytosol. Note=Diffusely distributed throughout the cytosol.;
[Isoform 2]: Endomembrane system. Note=Predominantly localized to cytosolic organelles.
Mouse PG classificationNA
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