| Gene Information | |
|---|---|
| Gene Name | GDD1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 913 |
| Protein Names | Anoctamin-5 (Gnathodiaphyseal dysplasia 1 protein) (Transmembrane protein 16E) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q75V66 |
| Gene Card | ANO5 |
| Uniprot ID | Q75V66 |
| Pfam | PF16178; PF04547 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in brain, heart, kidney, lung, and skeletal muscle. Weakly expressed in bone marrow, fetal liver, placenta, spleen, thymus, osteoblasts and periodontal ligament cells. {ECO:0000269|PubMed:15067359, ECO:0000269|PubMed:15124103}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs143777403 rs886043577 rs201725369 rs34994927 rs115750596 rs78266558 rs137854523 rs377553546 rs745908606 rs138144479 rs7481951 rs119103234 rs119103234 rs141799673 rs281865467 rs139618850 rs375014127 rs137854526 rs1422717390 rs760137559 rs200631556 rs137854529 rs61910685 rs1233836740 rs766853141 rs142073798 rs34969327 rs148293985 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:15124103}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000269|PubMed:20056604, ECO:0000269|PubMed:22946059}; Multi-pass membrane protein {ECO:0000255}. Note=Colocalized with CALR/calreticulin (PubMed:15124103). Shows an intracellular localization according to PubMed:22075693. {ECO:0000269|PubMed:15124103, ECO:0000269|PubMed:22075693}. |
| Mouse PG classification | NA |
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